InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AMT

Summary

InnateDB Protein

IDBP-698758.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AMT

Protein Name

Aminomethyltransferase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002992

InnateDB Gene

IDBG-645994 (AMT)

Protein Structure

UniProt Annotation

Function

The glycine cleavage system catalyzes the degradation of glycine.

Subcellular Localization

Mitochondrion.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004047	aminomethyltransferase activity
GO:0008483	transaminase activity
GO:0016740	transferase activity
GO:0031405	lipoic acid binding

Biological Process

GO:0006546	glycine catabolic process
GO:0032259	methylation

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006222 Glycine cleavage T-protein, N-terminal
IPR006223 Glycine cleavage system T protein
IPR013977 Glycine cleavage T-protein, C-terminal barrel domain
IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA
IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain

PFAM

PF01571
PF08669

PRINTS

PIRSF

PIRSF006487

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P25285