InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KLF9

Summary

InnateDB Protein

IDBP-69882.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KLF9

Protein Name

Kruppel-like factor 9

Synonyms

BTEB; BTEB1;

Species

Homo sapiens

Ensembl Protein

ENSP00000366330

InnateDB Gene

IDBG-69880 (KLF9)

Protein Structure

UniProt Annotation

Function

Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	5 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007566	embryo implantation
GO:0050847	progesterone receptor signaling pathway
GO:0097067	cellular response to thyroid hormone stimulus