InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HARS

Summary

InnateDB Protein

IDBP-698859.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HARS

Protein Name

Histidyl-tRNA synthetase, cytoplasmic

Synonyms

HARSL;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025094

InnateDB Gene

IDBG-646076 (HARS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004821	histidine-tRNA ligase activity
GO:0005524	ATP binding
GO:0016874	ligase activity

Biological Process

GO:0006412	translation
GO:0006418	tRNA aminoacylation for protein translation
GO:0006427	histidyl-tRNA aminoacylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000738 WHEP-TRS
IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR004154 Anticodon-binding
IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR009068 S15/NS1, RNA-binding
IPR015807 Histidine-tRNA ligase

PFAM

PF00458
PF00587
PF03129

PRINTS

PIRSF

PIRSF001549

SMART

SM00991

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt