InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GNPDA1

Summary

InnateDB Protein

IDBP-698901.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNPDA1

Protein Name

Glucosamine-6-phosphate isomerase 1

Synonyms

GNPI;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010347

InnateDB Gene

IDBG-646126 (GNPDA1)

Protein Structure

UniProt Annotation

Function

Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004342	glucosamine-6-phosphate deaminase activity
GO:0016787	hydrolase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006043	glucosamine catabolic process
GO:0006044	N-acetylglucosamine metabolic process
GO:0006091	generation of precursor metabolites and energy

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004547 Glucosamine-6-phosphate isomerase
IPR006148 Glucosamine/galactosamine-6-phosphate isomerase

PFAM

PF01182

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A4FV08

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

522919

UniGene

Bt.76406

RefSeq

NP_001073756

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC123566

GenPept

AAI23567