InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PLXNB1

Summary

InnateDB Protein

IDBP-698924.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLXNB1

Protein Name

plexin B1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017840

InnateDB Gene

IDBG-646138 (PLXNB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0032794	GTPase activating protein binding

Biological Process

GO:0007162	negative regulation of cell adhesion
GO:0007165	signal transduction
GO:0007275	multicellular organismal development
GO:0008360	regulation of cell shape
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0032321	positive regulation of Rho GTPase activity
GO:0033689	negative regulation of osteoblast proliferation
GO:0043931	ossification involved in bone maturation
GO:0048812	neuron projection morphogenesis
GO:0050772	positive regulation of axonogenesis
GO:0051493	regulation of cytoskeleton organization
GO:0071526	semaphorin-plexin signaling pathway
GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis

Cellular Component

GO:0002116	semaphorin receptor complex
GO:0005622	intracellular
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001627 Sema domain
IPR002165 Plexin
IPR002909 IPT domain
IPR008936 Rho GTPase activation protein
IPR013548 Plexin, cytoplasmic RasGAP domain
IPR014756 Immunoglobulin E-set
IPR016201 Plexin-like fold

PFAM

PF01403
PF01437
PF01833
PF08337

PRINTS

PIRSF

SMART

SM00630
SM00429
SM00423

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite