InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GJD2

Summary

InnateDB Protein

IDBP-698943.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GJD2

Protein Name

Gap junction delta-2 protein

Synonyms

Cx36; GJA9;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028966

InnateDB Gene

IDBG-646168 (GJD2)

Protein Structure

UniProt Annotation

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001508	action potential
GO:0007154	cell communication
GO:0007267	cell-cell signaling
GO:0007268	synaptic transmission
GO:0007601	visual perception

Cellular Component

GO:0005886	plasma membrane
GO:0005921	gap junction
GO:0005922	connexon complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction

Protein Structure and Domains

PDB ID

InterPro

IPR000500 Connexin
IPR002260 Gap junction delta-2 protein (Cx36)
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain

PFAM

PF00029
PF10582

PRINTS

PR00206
PR01131

PIRSF

SMART

SM00037
SM01089

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q866T7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

282577

UniGene

Bt.12535

RefSeq

NP_777108

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AY150575

GenPept

AAN37413