Version 5.4
Homo sapiens Protein: ST6GALNAC1
Summary
InnateDB Protein IDBP-69901.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST6GALNAC1
Protein Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000156626
InnateDB Gene IDBG-69899 (ST6GALNAC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0009312 oligosaccharide biosynthetic process
GO:0097503 sialylation
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001675 Glycosyl transferase, family 29
PFAM PF00777
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NSC7
PhosphoSite PhosphoSite-Q9NSC7
TrEMBL
UniProt Splice Variant
Entrez Gene 55808
UniGene Hs.608531
RefSeq NP_060884
HUGO HGNC:23614
OMIM 610138
CCDS CCDS11748
HPRD 15340
IMGT
EMBL AY096001 AY358918 Y11339 Y11340
GenPept AAM22800 AAQ89277 CAA72179 CAA72180

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca