InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PDE6A

Summary

InnateDB Protein

IDBP-699035.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDE6A

Protein Name

rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000036518

InnateDB Gene

IDBG-646244 (PDE6A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0008081	phosphoric diester hydrolase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity

Biological Process

GO:0007165	signal transduction
GO:0046037	GMP metabolic process
GO:0051480	cytosolic calcium ion homeostasis
GO:0060041	retina development in camera-type eye

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003018 GAF domain
IPR003607 HD/PDEase domain
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
IPR029016 GAF domain-like

PFAM

PF00233
PF01590
PF13185
PF13492

PRINTS

PR00387

PIRSF

SMART

SM00065
SM00471

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt