Version 5.4
Bos taurus Protein: FAM82A2
Summary
InnateDB Protein IDBP-699041.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM82A2
Protein Name Regulator of microtubule dynamics protein 3
Synonyms FAM82A2; FAM82C;
Species Bos taurus
Ensembl Protein ENSBTAP00000003795
InnateDB Gene IDBG-646258 (FAM82A2)
Protein Structure
UniProt Annotation
Function Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006874 cellular calcium ion homeostasis
GO:0006915 apoptotic process
GO:0030154 cell differentiation
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1JQC5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 514748
UniGene Bt.22185
RefSeq NP_001069147
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116057
GenPept AAI16058

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca