Bos taurus Protein: RHOV | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-699056.2 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | RHOV | ||||||||||
Protein Name | Rho-related GTP-binding protein RhoV | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Protein | ENSBTAP00000021672 | ||||||||||
InnateDB Gene | IDBG-646270 (RHOV) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway. {ECO:0000250UniProtKB:Q9Z1Y0}. | ||||||||||
Subcellular Localization | Cell membrane {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}; Lipid-anchor {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}; Cytoplasmic side {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}. Endosome membrane {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}; Lipid-anchor {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}; Cytoplasmic side {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}. Note=Treatment with TNF activates endosomal but not plasma membrane RHOV. {ECO:0000250UniProtKB:P61586, ECO:0000250UniProtKB:Q9Z1Y0}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR001806
Small GTPase superfamily IPR003578 Small GTPase superfamily, Rho type IPR003579 Small GTPase superfamily, Rab type IPR005225 Small GTP-binding protein domain IPR013684 Mitochondrial Rho-like IPR020849 Small GTPase superfamily, Ras type IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF00071
PF08477 |
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PRINTS |
PR00449
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PIRSF | |||||||||||
SMART |
SM00174
SM00175 SM00173 |
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q17QI8 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | F1N282 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 538143 | ||||||||||
UniGene | Bt.61724 | ||||||||||
RefSeq | NP_001069567 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC118335 DAAA02028555 | ||||||||||
GenPept | AAI18336 | ||||||||||