Version 5.4
Bos taurus Protein: SACM1L
Summary
InnateDB Protein IDBP-699060.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SACM1L
Protein Name Phosphatidylinositide phosphatase SAC1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004549
InnateDB Gene IDBG-646269 (SACM1L)
Protein Structure
UniProt Annotation
Function Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2 (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0042578 phosphoric ester hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0016311 dephosphorylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR002013 Synaptojanin, N-terminal
PFAM PF02383
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6QL88
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 530577
UniGene Bt.69923
RefSeq NP_001095601
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC147878
GenPept AAI47879

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca