InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: INO80

Summary

InnateDB Protein

IDBP-699068.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INO80

Protein Name

INO80 homolog (S. cerevisiae)

Synonyms

INOC1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013708

InnateDB Gene

IDBG-646279 (INO80)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016817	hydrolase activity, acting on acid anhydrides
GO:0016887	ATPase activity
GO:0043014	alpha-tubulin binding

Biological Process

GO:0000070	mitotic sister chromatid segregation
GO:0000724	double-strand break repair via homologous recombination
GO:0006200	ATP catabolic process
GO:0006302	double-strand break repair
GO:0006338	chromatin remodeling
GO:0010571	positive regulation of nuclear cell cycle DNA replication
GO:0030307	positive regulation of cell growth
GO:0032508	DNA duplex unwinding
GO:0034644	cellular response to UV
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051225	spindle assembly
GO:0070914	UV-damage excision repair
GO:0071479	cellular response to ionizing radiation
GO:2000045	regulation of G1/S transition of mitotic cell cycle

Cellular Component

GO:0005634	nucleus
GO:0031011	Ino80 complex

Protein Structure and Domains

PDB ID

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite