Version 5.4
Bos taurus Protein: TSEN2
Summary
InnateDB Protein IDBP-699193.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSEN2
Protein Name tRNA-splicing endonuclease subunit Sen2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000041558
InnateDB Gene IDBG-646389 (TSEN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000213 tRNA-intron endonuclease activity
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000214 tRNA-intron endonuclease complex
Protein Structure and Domains
PDB ID
InterPro IPR006677 tRNA intron endonuclease, catalytic domain-like
IPR006678 tRNA intron endonuclease, N-terminal
IPR016589 tRNA-splicing endonuclease, SEN2 subunit
PFAM PF01974
PF02778
PRINTS
PIRSF PIRSF011789
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1PS46
UniProt Splice Variant
Entrez Gene 515511
UniGene
RefSeq NP_001035942
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AH015382 BC146215 DAAA02054586 DAAA02054587 DAAA02054588
GenPept AAI46216 ABB82241

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca