InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PPIB

Summary

InnateDB Protein

IDBP-699307.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPIB

Protein Name

Peptidyl-prolyl cis-trans isomerase B

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022378

InnateDB Gene

IDBG-646495 (PPIB)

Protein Structure

UniProt Annotation

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Subcellular Localization

Endoplasmic reticulum lumen. Melanosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0016853	isomerase activity
GO:0032403	protein complex binding
GO:0042277	peptide binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0006457	protein folding
GO:0040018	positive regulation of multicellular organism growth
GO:0050821	protein stabilization
GO:0060348	bone development
GO:0061077	chaperone-mediated protein folding

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0016020	membrane
GO:0032991	macromolecular complex
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome