Version 5.4
| Bos taurus Protein: FBXL22 | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-699335.2 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | FBXL22 | ||||
| Protein Name | F-box/LRR-repeat protein 22 | ||||
| Synonyms | |||||
| Species | Bos taurus | ||||
| Ensembl Protein | ENSBTAP00000011600 | ||||
| InnateDB Gene | IDBG-646523 (FBXL22) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC) (By similarity). {ECO:0000250}. | ||||
| Subcellular Localization | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. | ||||
| Disease Associations | |||||
| Tissue Specificity | |||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR001810
F-box domain IPR006553 Leucine-rich repeat, cysteine-containing subtype |
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| PFAM |
PF00646
PF12937 PF13013 |
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| PRINTS | |||||
| PIRSF | |||||
| SMART |
SM00256
SM00367 |
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| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q2HJF2 | ||||
| PhosphoSite | PhosphoSite- | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 513821 | ||||
| UniGene | Bt.61733 | ||||
| RefSeq | NP_001039621 | ||||
| HUGO | |||||
| OMIM | |||||
| CCDS | |||||
| HPRD | |||||
| IMGT | |||||
| EMBL | BC105485 | ||||
| GenPept | AAI05486 | ||||