InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: USP3

Summary

InnateDB Protein

IDBP-699347.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

USP3

Protein Name

ubiquitin thiolesterase 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011598

InnateDB Gene

IDBG-646524 (USP3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004221	ubiquitin thiolesterase activity
GO:0008233	peptidase activity
GO:0008234	cysteine-type peptidase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0036459	ubiquitinyl hydrolase activity
GO:0042393	histone binding
GO:0046872	metal ion binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0006281	DNA repair
GO:0006508	proteolysis
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016578	histone deubiquitination
GO:0031647	regulation of protein stability

Cellular Component

GO:0000790

nuclear chromatin

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR001607 Zinc finger, UBP-type
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF00443
PF02148

PRINTS

PIRSF

SMART

SM00290

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite