Version 5.4
Bos taurus Protein: HDC
Summary
InnateDB Protein IDBP-699492.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HDC
Protein Name Histidine decarboxylase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000013083
InnateDB Gene IDBG-646667 (HDC)
Protein Structure
UniProt Annotation
Function Catalyzes the biosynthesis of histamine from histidine. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004398 histidine decarboxylase activity
GO:0016829 lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0001694 histamine biosynthetic process
GO:0006520 cellular amino acid metabolic process
GO:0006548 histidine catabolic process
GO:0019752 carboxylic acid metabolic process
GO:0042423 catecholamine biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002129 Pyridoxal phosphate-dependent decarboxylase
IPR010977 Aromatic-L-amino-acid decarboxylase
IPR015424 Pyridoxal phosphate-dependent transferase
PFAM PF00282
PRINTS PR00800
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5EA83
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 515950
UniGene
RefSeq NP_001019722
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT020686
GenPept AAX08703

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca