InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.25242

Summary

InnateDB Protein

IDBP-699554.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.25242

Protein Name

MHD domain-containing death-inducing protein

Synonyms

C14orf108; Mu5; MUDENG;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017337

InnateDB Gene

IDBG-646726 (BT.25242)

Protein Structure

UniProt Annotation

Function

As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol. Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lysosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=May cycle on and off membranes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0016197	endosomal transport

Cellular Component

GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005770	late endosome
GO:0005829	cytosol
GO:0016020	membrane
GO:0030119	AP-type membrane coat adaptor complex
GO:0030131	clathrin adaptor complex
GO:0031902	late endosome membrane

Protein Structure and Domains

PDB ID

InterPro

IPR008968 Clathrin adaptor, mu subunit, C-terminal
IPR028565 Mu homology domain

PFAM

PF00928

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9X5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

539663

UniGene

Bt.25242

RefSeq

NP_001015670

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BT020795

GenPept

AAX08812