Version 5.4
Bos taurus Protein: ISCA2
Summary
InnateDB Protein IDBP-699693.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISCA2
Protein Name Iron-sulfur cluster assembly 2 homolog, mitochondrial
Synonyms HBLD1;
Species Bos taurus
Ensembl Protein ENSBTAP00000029272
InnateDB Gene IDBG-646854 (ISCA2)
Protein Structure
UniProt Annotation
Function Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000361 FeS cluster biogenesis
IPR016092 FeS cluster insertion protein
PFAM PF01521
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TBG7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 613290
UniGene Bt.56897
RefSeq NP_001033772
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110251
GenPept AAI10252

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca