InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DLST

Summary

InnateDB Protein

IDBP-699699.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DLST

Protein Name

dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000008473

InnateDB Gene

IDBG-646860 (DLST)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups

Biological Process

GO:0006099	tricarboxylic acid cycle
GO:0008152	metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0016020	membrane
GO:0045252	oxoglutarate dehydrogenase complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000089 Biotin/lipoyl attachment
IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain
IPR006255 Dihydrolipoamide succinyltransferase
IPR011053 Single hybrid motif

PFAM

PF00364
PF00198

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MEQ3

UniProt Splice Variant

Entrez Gene

506888

UniGene

RefSeq

NP_001068750

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02029614 DAAA02029615 DAAA02029616 DAAA02029617

GenPept