Version 5.4
Bos taurus Protein: DIO2
Summary
InnateDB Protein IDBP-699754.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIO2
Protein Name type II iodothyronine deiodinase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002107
InnateDB Gene IDBG-646906 (DIO2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004800 thyroxine 5'-deiodinase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0042404 thyroid hormone catabolic process
GO:0042446 hormone biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000643 Iodothyronine deiodinase
PFAM PF00837
PRINTS
PIRSF PIRSF001330
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5I3B0
UniProt Splice Variant
Entrez Gene 494548
UniGene Bt.63066
RefSeq NP_001010992
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AH014576 DAAA02029819
GenPept AAW51122

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca