Version 5.4
Homo sapiens Protein: ELMOD1
Summary
InnateDB Protein IDBP-70017.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELMOD1
Protein Name ELMO/CED-12 domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000265840
InnateDB Gene IDBG-70015 (ELMOD1)
Protein Structure
UniProt Annotation
Function Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. {ECO:0000269PubMed:17452337}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0006909 phagocytosis
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR006816 Engulfment/cell motility, ELMO
PFAM PF04727
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N336
PhosphoSite PhosphoSite-
TrEMBL E9PLM8
UniProt Splice Variant
Entrez Gene 643923
UniGene Hs.730145
RefSeq NP_061182
HUGO HGNC:25334
OMIM 615456
CCDS CCDS44723
HPRD 10934
IMGT
EMBL AK303689 AL359601 AP000889 AP002353 BC028725 CH471065
GenPept AAH28725 BAG64679 CAB94879 EAW67091

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca