Version 5.4
Bos taurus Protein: RPRM
Summary
InnateDB Protein IDBP-700546.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPRM
Protein Name Protein reprimo
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028688
InnateDB Gene IDBG-647748 (RPRM)
Protein Structure
UniProt Annotation
Function May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007050 cell cycle arrest
GO:0007346 regulation of mitotic cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1RMT2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614739
UniGene Bt.22279
RefSeq NP_001074208
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114727
GenPept AAI14728

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca