Bos taurus Protein: MC5R | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-700782.2 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | MC5R | ||||||||||
Protein Name | Melanocortin receptor 5 | ||||||||||
Synonyms | MC5; | ||||||||||
Species | Bos taurus | ||||||||||
Ensembl Protein | ENSBTAP00000012049 | ||||||||||
InnateDB Gene | IDBG-648012 (MC5R) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR000621 Melanocortin 5 receptor IPR001671 Melanocortin/ACTH receptor IPR001908 Melanocortin receptor IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx |
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PFAM |
PF00001
PF10320 |
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PRINTS |
PR00237
PR01063 PR00534 PR00535 |
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PIRSF | |||||||||||
SMART | |||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | P56451 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 507987 | ||||||||||
UniGene | Bt.45037 | ||||||||||
RefSeq | NP_001015542 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AJ002024 | ||||||||||
GenPept | CAA05147 | ||||||||||