InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GPR4

Summary

InnateDB Protein

IDBP-700868.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPR4

Protein Name

G-protein coupled receptor 4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000024480

InnateDB Gene

IDBG-648102 (GPR4)

Protein Structure

UniProt Annotation

Function

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production. {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR002276 G protein-coupled receptor 4 orphan
IPR005464 Psychosine receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10323
PF10328

PRINTS

PR00237
PR01147
PR01649

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1JQB3