InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.53878

Summary

InnateDB Protein

IDBP-701163.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.53878

Protein Name

potassium voltage-gated channel subfamily A member 5

Synonyms

Kv1.5;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009938

InnateDB Gene

IDBG-648415 (BT.53878)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0015271	outward rectifier potassium channel activity
GO:0019870	potassium channel inhibitor activity
GO:0019901	protein kinase binding
GO:0051393	alpha-actinin binding
GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0097110	scaffold protein binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0019229	regulation of vasoconstriction
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0043266	regulation of potassium ion transport
GO:0043267	negative regulation of potassium ion transport
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0060081	membrane hyperpolarization
GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
GO:0071435	potassium ion export
GO:0071805	potassium ion transmembrane transport
GO:0086014	atrial cardiac muscle cell action potential
GO:0086091	regulation of heart rate by cardiac conduction

Cellular Component

GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex
GO:0014704	intercalated disc
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045121	membrane raft

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR003091 Potassium channel
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR003968 Potassium channel, voltage dependent, Kv
IPR003972 Potassium channel, voltage dependent, Kv1
IPR004052 Potassium channel, voltage dependent, Kv1.5
IPR005821 Ion transport domain
IPR011333 BTB/POZ fold
IPR013099 Two pore domain potassium channel domain
IPR013122 Polycystin cation channel, PKD1/PKD2

PFAM

PF02214
PF00520
PF07885
PF08016

PRINTS

PR00169
PR01491
PR01496
PR01512

PIRSF

SMART

SM00225

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt