InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ASCL1

Summary

InnateDB Protein

IDBP-701275.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASCL1

Protein Name

achaete-scute complex homolog 1 (Drosophila)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021592

InnateDB Gene

IDBG-648540 (ASCL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000989	transcription factor binding transcription factor activity
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043425	bHLH transcription factor binding
GO:0043565	sequence-specific DNA binding
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0001764	neuron migration
GO:0003358	noradrenergic neuron development
GO:0003359	noradrenergic neuron fate commitment
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007219	Notch signaling pathway
GO:0007346	regulation of mitotic cell cycle
GO:0007389	pattern specification process
GO:0007400	neuroblast fate determination
GO:0007405	neuroblast proliferation
GO:0008593	regulation of Notch signaling pathway
GO:0010001	glial cell differentiation
GO:0010468	regulation of gene expression
GO:0014003	oligodendrocyte development
GO:0021527	spinal cord association neuron differentiation
GO:0021529	spinal cord oligodendrocyte cell differentiation
GO:0021530	spinal cord oligodendrocyte cell fate specification
GO:0021750	vestibular nucleus development
GO:0021779	oligodendrocyte cell fate commitment
GO:0021892	cerebral cortex GABAergic interneuron differentiation
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain
GO:0021954	central nervous system neuron development
GO:0021987	cerebral cortex development
GO:0022008	neurogenesis
GO:0030154	cell differentiation
GO:0030182	neuron differentiation
GO:0030856	regulation of epithelial cell differentiation
GO:0032526	response to retinoic acid
GO:0042127	regulation of cell proliferation
GO:0043066	negative regulation of apoptotic process
GO:0043525	positive regulation of neuron apoptotic process
GO:0045665	negative regulation of neuron differentiation
GO:0045666	positive regulation of neuron differentiation
GO:0045747	positive regulation of Notch signaling pathway
GO:0045787	positive regulation of cell cycle
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048469	cell maturation
GO:0048663	neuron fate commitment
GO:0048665	neuron fate specification
GO:0048666	neuron development
GO:0048699	generation of neurons
GO:0048709	oligodendrocyte differentiation
GO:0050767	regulation of neurogenesis
GO:0050769	positive regulation of neurogenesis
GO:0050883	musculoskeletal movement, spinal reflex action
GO:0060163	subpallium neuron fate commitment
GO:0060165	regulation of timing of subpallium neuron differentiation
GO:0060166	olfactory pit development
GO:0060579	ventral spinal cord interneuron fate commitment
GO:0061100	lung neuroendocrine cell differentiation
GO:0061102	stomach neuroendocrine cell differentiation
GO:0061103	carotid body glomus cell differentiation
GO:0061104	adrenal chromaffin cell differentiation
GO:0061549	sympathetic ganglion development
GO:2000179	positive regulation of neural precursor cell proliferation