Version 5.4
Bos taurus Protein: DENR
Summary
InnateDB Protein IDBP-701402.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENR
Protein Name Density-regulated protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000046224
InnateDB Gene IDBG-648679 (DENR)
Protein Structure
UniProt Annotation
Function May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001950 Translation initiation factor SUI1
IPR005873 Density-regulated protein DRP1
PFAM PF01253
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2HJ47
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 785243
UniGene Bt.88754
RefSeq NP_001039993
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113316
GenPept AAI13317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca