Version 5.4
Bos taurus Protein: FAHD1
Summary
InnateDB Protein IDBP-701412.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAHD1
Protein Name Fumarylacetoacetate hydrolase domain-containing protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000044120
InnateDB Gene IDBG-648694 (FAHD1)
Protein Structure
UniProt Annotation
Function Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018773 acetylpyruvate hydrolase activity
GO:0034545 fumarylpyruvate hydrolase activity
GO:0046872 metal ion binding
GO:0047621 acylpyruvate hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR002529 Fumarylacetoacetase, C-terminal
IPR011234 Fumarylacetoacetase, C-terminal-related
PFAM PF01557
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2HJ98
PhosphoSite PhosphoSite-
TrEMBL M5FKD8
UniProt Splice Variant
Entrez Gene 509273
UniGene Bt.70710
RefSeq NP_001068868
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC113240 GJ062847
GenPept AAI13241 DAA15562

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca