InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DOLK

Summary

InnateDB Protein

IDBP-701755.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DOLK

Protein Name

Dolichol kinase

Synonyms

TMEM15;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054607

InnateDB Gene

IDBG-649070 (DOLK)

Protein Structure

UniProt Annotation

Function

Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004168	dolichol kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity

Biological Process

GO:0016310	phosphorylation
GO:0043048	dolichyl monophosphate biosynthetic process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030176	integral component of endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q58CR4

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

526844

UniGene

Bt.8925

RefSeq

NP_001030442

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC126569 BT021510 BT021883

GenPept

AAI26570 AAX46357 AAX46730