InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NEUROD2

Summary

InnateDB Protein

IDBP-701810.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEUROD2

Protein Name

neurogenic differentiation 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005381

InnateDB Gene

IDBG-649127 (NEUROD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0001662	behavioral fear response
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0007399	nervous system development
GO:0008306	associative learning
GO:0016567	protein ubiquitination
GO:0021695	cerebellar cortex development
GO:0030154	cell differentiation
GO:0031915	positive regulation of synaptic plasticity
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048666	neuron development
GO:0050850	positive regulation of calcium-mediated signaling
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0071257	cellular response to electrical stimulus
GO:0071277	cellular response to calcium ion
GO:0090129	positive regulation of synapse maturation
GO:2000297	negative regulation of synapse maturation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR016637 Transcription factor, basic helix-loop-helix, NeuroD
IPR022575 Neurogenic differentiation factor, domain of unknown function

PFAM

PF00010
PF12533

PRINTS

PIRSF

PIRSF015618

SMART

SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt