InnateDB Protein
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IDBP-701834.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MT-ND4
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Protein Name
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NADH-ubiquinone oxidoreductase chain 4
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000053150
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InnateDB Gene
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IDBG-649169 (MT-ND4)
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Protein Structure
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Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
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Subcellular Localization |
Mitochondrion membrane {ECO:0000269PubMed:17060615}; Multi-pass membrane protein {ECO:0000269PubMed:17060615}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
Accession |
GO Term |
GO:0008137
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NADH dehydrogenase (ubiquinone) activity
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GO:0016491
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oxidoreductase activity
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Biological Process |
GO:0006120
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mitochondrial electron transport, NADH to ubiquinone
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GO:0042773
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ATP synthesis coupled electron transport
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GO:0055114
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oxidation-reduction process
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Cellular Component |
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PDB ID |
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InterPro |
IPR000260
NADH:ubiquinone oxidoreductase, chain 4, N-terminal
IPR001750
NADH:ubiquinone/plastoquinone oxidoreductase
IPR003918
NADH:ubiquinone oxidoreductase
IPR010227
NADH-quinone oxidoreductase, chain M/4
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PFAM |
PF01059
PF00361
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PRINTS |
PR01437
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P03910
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q7JAS7
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UniProt Splice Variant |
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Entrez Gene |
3283886
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UniGene |
Bt.103193
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RefSeq |
YP_209214
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB074962
AB074963
AB074964
AB074965
AB074966
AB074967
AB074968
AF490528
AF490529
AF492351
AF493541
AF493542
AY308066
AY308067
AY308068
AY526085
AY676855
AY676856
AY676857
AY676858
AY676859
AY676860
AY676861
AY676862
AY676863
AY676864
AY676865
AY676866
AY676867
AY676868
AY676869
AY676870
AY676871
AY676872
AY676873
DQ124371
DQ124372
DQ124373
DQ124375
DQ124376
DQ124377
DQ124378
DQ124379
DQ124380
DQ124381
DQ124382
DQ124383
DQ124384
DQ124385
DQ124386
DQ124387
DQ124388
DQ124390
DQ124391
DQ124392
DQ124393
DQ124394
DQ124395
DQ124396
DQ124397
DQ124398
DQ124399
DQ124400
DQ124401
DQ124402
DQ124404
DQ124406
DQ124407
DQ124408
DQ124409
DQ124410
DQ124411
DQ124412
DQ124413
DQ124414
DQ124415
DQ124416
DQ124417
DQ124418
DQ347619
EU177815
EU177816
EU177817
EU177818
EU177819
EU177820
EU177821
EU177822
EU177823
EU177824
EU177825
EU177826
EU177828
EU177829
EU177830
EU177831
EU177832
EU177833
EU177834
EU177835
EU177836
EU177837
EU177838
EU177839
EU177840
EU177841
EU177842
EU177843
EU177844
EU177845
EU177846
EU177847
EU177848
EU177849
EU177850
EU177851
EU177852
EU177853
EU177854
EU177855
EU177856
EU177858
EU177859
EU177860
EU177861
EU177862
EU177863
EU177864
EU177865
EU177866
EU177867
FJ971080
FJ971081
GQ129207
GQ129208
GU947007
GU947008
GU947009
GU947010
GU947011
GU947012
GU947013
GU947014
GU947015
GU947016
GU947017
GU947018
GU947019
GU947020
GU947021
HM045018
HQ025805
HQ184030
HQ184031
HQ184032
HQ184033
HQ184036
HQ184037
HQ184038
HQ184039
JN817300
JN817301
JN817306
JN817307
JN817308
JN817309
JN817310
JN817312
JN817313
JN817314
JN817315
JN817317
JN817318
JN817319
JN817320
JN817321
JN817322
JN817323
JN817324
JN817326
JN817327
JN817328
JN817329
JN817332
JN817333
JN817334
JN817335
JN817336
JN817337
JN817338
JN817339
JN817340
JN817341
JN817342
JN817343
JN817344
JN817345
JN817346
JN817347
JN817348
JN817349
JN817350
JN817351
JQ967333
KC153972
KC153973
KC153974
KC153975
KC153976
KC153977
KF163061
KF163062
KF163063
KF163064
KF163065
KF163066
KF163067
KF163068
KF163069
KF163070
KF163071
KF163073
KF163074
KF163075
KF163076
KF163077
KF163078
KF163079
KF163080
KF163081
KF163082
KF163083
KF163084
KF163085
KF163086
KF163087
KF163088
KF163089
KF163090
KF163091
KF163092
KF163093
KF163094
KF926377
V00654
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GenPept |
AAM08326
AAM08339
AAM12798
AAM12811
AAP47837
AAP47850
AAP47863
AAQ06602
AAS18251
AAV88119
AAV88132
AAV88145
AAV88158
AAV88171
AAV88184
AAV88197
AAV88210
AAV88223
AAV88236
AAV88249
AAV88262
AAV88275
AAV88288
AAV88301
AAV88314
AAV88327
AAV88340
AAV88353
AAZ16529
AAZ16542
AAZ16555
AAZ16581
AAZ16594
AAZ16607
AAZ16620
AAZ16633
AAZ16646
AAZ16659
AAZ16672
AAZ16685
AAZ16698
AAZ16711
AAZ16724
AAZ16737
AAZ16750
AAZ16776
AAZ16789
AAZ16802
AAZ16815
AAZ16828
AAZ16841
AAZ16854
AAZ16867
AAZ16880
AAZ16893
AAZ16906
AAZ16919
AAZ16932
AAZ16958
AAZ16984
AAZ16997
AAZ17010
AAZ17023
AAZ17036
AAZ17049
AAZ17062
AAZ17075
AAZ17088
AAZ17101
AAZ17114
AAZ17127
AAZ17140
ABC84253
ABV70214
ABV70227
ABV70240
ABV70253
ABV70266
ABV70279
ABV70292
ABV70305
ABV70318
ABV70331
ABV70344
ABV70357
ABV70383
ABV70396
ABV70409
ABV70422
ABV70435
ABV70448
ABV70461
ABV70474
ABV70487
ABV70500
ABV70513
ABV70526
ABV70539
ABV70552
ABV70565
ABV70578
ABV70591
ABV70604
ABV70617
ABV70630
ABV70643
ABV70656
ABV70669
ABV70682
ABV70695
ABV70708
ABV70721
ABV70734
ABV70747
ABV70773
ABV70786
ABV70799
ABV70812
ABV70825
ABV70838
ABV70851
ABV70864
ABV70877
ABV70890
ACQ73758
ACQ73771
ACR19416
ACR19429
ADF29606
ADF49336
ADF49349
ADF49362
ADF49375
ADF49388
ADF49401
ADF49414
ADF49427
ADF49440
ADF49453
ADF49466
ADF49479
ADF49492
ADF49505
ADF49518
ADM35744
ADN11784
ADN11797
ADN11810
ADN11823
ADN11862
ADN11875
ADN11888
ADN11901
AER53683
AER53696
AER53761
AER53774
AER53787
AER53800
AER53813
AER53839
AER53852
AER53865
AER53878
AER53904
AER53917
AER53930
AER53943
AER53956
AER53969
AER53982
AER53995
AER54021
AER54034
AER54047
AER54060
AER54099
AER54112
AER54125
AER54138
AER54151
AER54164
AER54177
AER54190
AER54203
AER54216
AER54229
AER54242
AER54255
AER54268
AER54281
AER54294
AER54307
AER54320
AER54333
AER54346
AFK75893
AGB56907
AGB56920
AGB56933
AGB56946
AGB56959
AGB56972
AGU00427
AGU00440
AGU00453
AGU00466
AGU00479
AGU00492
AGU00505
AGU00518
AGU00531
AGU00544
AGU00557
AGU00583
AGU00596
AGU00609
AGU00622
AGU00635
AGU00648
AGU00661
AGU00674
AGU00687
AGU00700
AGU00713
AGU00726
AGU00739
AGU00752
AGU00765
AGU00778
AGU00791
AGU00804
AGU00817
AGU00830
AGU00843
AGU00856
AHI51994
BAC54744
BAC54757
BAC54770
BAC54783
BAC54796
BAC54809
BAC54822
CAA24009
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