Version 5.4
Homo sapiens Protein: TNRC6C
Summary
InnateDB Protein IDBP-70323.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNRC6C
Protein Name trinucleotide repeat containing 6C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000336783
InnateDB Gene IDBG-70319 (TNRC6C)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0001706 endoderm formation
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007219 Notch signaling pathway
GO:0007492 endoderm development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010467 gene expression
GO:0035162 embryonic hemopoiesis
GO:0035278 negative regulation of translation involved in gene silencing by miRNA
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048568 embryonic organ development
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060964 regulation of gene silencing by miRNA
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR009060 UBA-like
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
IPR019486 Argonaute hook domain
PFAM PF00627
PF10427
PRINTS
PIRSF
SMART SM00165
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HCJ0
PhosphoSite PhosphoSite-Q9HCJ0
TrEMBL K7ELY5
UniProt Splice Variant
Entrez Gene 57690
UniGene Hs.722937
RefSeq NP_001136112
HUGO HGNC:29318
OMIM 610741
CCDS CCDS45799
HPRD 10026
IMGT
EMBL AB046802 AC015804 AC021593 AK056421 AL834429 BC045631 CH471099
GenPept AAH45631 BAB13408 BAB71179 CAD39090 EAW89480

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca