InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fkbp2

Summary

InnateDB Protein

IDBP-704509.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fkbp2

Protein Name

Synonyms

13kDa; FKBP-2; mFKBP13; mFKBP2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000136438

InnateDB Gene

IDBG-137677 (Fkbp2)

Protein Structure

UniProt Annotation

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005528	FK506 binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0006457	protein folding
GO:0018208	peptidyl-proline modification

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:95542

InterPro

IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain

PFAM

PF00254

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P45878

PhosphoSite

PhosphoSite-P45878

TrEMBL

Q3TND1

UniProt Splice Variant

Entrez Gene

14227

UniGene

RefSeq

NP_001159840

MGI ID

MGI Symbol

Fkbp2

OMIM

CCDS

CCDS29515

HPRD

IMGT

EMBL

AK165394 BC031824 BC053692 CH466612 M77831

GenPept

AAA37631 AAH31824 AAH53692 BAE38158 EDL33271 EDL33272 EDL33274