InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prpf19

Summary

InnateDB Protein

IDBP-705122.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prpf19

Protein Name

Synonyms

AA617263; AL024362; D19Wsu55e; NMP200; Prp19; PSO4; Snev;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000136858

InnateDB Gene

IDBG-145419 (Prpf19)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	81 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0034450	ubiquitin-ubiquitin ligase activity
GO:0042802	identical protein binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0000245	spliceosomal complex assembly
GO:0016567	protein ubiquitination

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0000974	Prp19 complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0016607	nuclear speck
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:106247

InterPro

IPR000772 Ricin B lectin domain
IPR001680 WD40 repeat
IPR003613 U box domain
IPR013915 Pre-mRNA-splicing factor 19
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00652
PF14200
PF00400
PF04564
PF08606

PRINTS

PR00320

PIRSF

SMART

SM00458
SM00320
SM00504

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt