InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDX10

Summary

InnateDB Protein

IDBP-70537.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX10

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 10

Synonyms

HRH-J8;

Species

Homo sapiens

Ensembl Protein

ENSP00000314348

InnateDB Gene

IDBG-70535 (DDX10)

Protein Structure

UniProt Annotation

Function

Putative ATP-dependent RNA helicase.

Subcellular Localization

Disease Associations

Tissue Specificity

High in testis but widely expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	5 [view]
Protein-DNA	7 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003724	RNA helicase activity
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006200	ATP catabolic process
GO:0008152	metabolic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13206