Version 5.4
Homo sapiens Protein: PRSS55
Summary
InnateDB Protein IDBP-7067.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRSS55
Protein Name protease, serine, 55
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000333003
InnateDB Gene IDBG-7065 (PRSS55)
Protein Structure
UniProt Annotation
Function Probable serine protease. {ECO:0000250}.
Subcellular Localization Isoform 1: Membrane {ECO:0000305}; Single- pass type I membrane protein {ECO:0000305}.Isoform 2: Cytoplasm, cytosol.
Disease Associations
Tissue Specificity Only detected in testis. Expressed in spermatogonia, spermatocytes, spermatids, Leydig and Sertoli cells. Expressed in prostate cancer and ovarian cancer (at protein level). {ECO:0000269PubMed:18844450, ECO:0000269PubMed:23436708}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
PFAM PF00089
PF09342
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UWB4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 203074
UniGene Hs.728701
RefSeq NP_940866
HUGO HGNC:30824
OMIM 615144
CCDS CCDS5976
HPRD 07162
IMGT
EMBL AC104964 AY358867 BC033497
GenPept AAQ89226

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca