InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ANKRD54

Summary

InnateDB Protein

IDBP-7075.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANKRD54

Protein Name

ankyrin repeat domain 54

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000215941

InnateDB Gene

IDBG-7073 (ANKRD54)

Protein Structure

UniProt Annotation

Function

Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Midbody {ECO:0000250}. Note=Shuttles between nucleus and cytoplasm during the cell cycle. EPO stimulation induces nuclear accumulation (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019887	protein kinase regulator activity
GO:0032403	protein complex binding

Biological Process

GO:0006913	nucleocytoplasmic transport
GO:0045648	positive regulation of erythrocyte differentiation
GO:0045859	regulation of protein kinase activity
GO:1902531	regulation of intracellular signal transduction