InnateDB Protein
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IDBP-7078.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TTYH3
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Protein Name
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tweety homolog 3 (Drosophila)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000258796
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InnateDB Gene
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IDBG-7076 (TTYH3)
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Protein Structure
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Function |
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. {ECO:0000269PubMed:15010458}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:15010458}; Multi-pass membrane protein {ECO:0000269PubMed:15010458}.
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Disease Associations |
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Tissue Specificity |
Expressed in excitable tissues. Expressed in the brain, heart, skeletal muscle, colon, spleen, kidney and peripheral blood leukocytes. {ECO:0000269PubMed:15010458}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005229
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intracellular calcium activated chloride channel activity
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GO:0005254
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chloride channel activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006990
Tweety
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PFAM |
PF04906
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9C0H2
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PhosphoSite |
PhosphoSite-Q9C0H2
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TrEMBL |
A0A024R816
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UniProt Splice Variant |
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Entrez Gene |
80727
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UniGene |
Hs.622255
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RefSeq |
NP_079526
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HUGO |
HGNC:22222
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OMIM |
608919
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CCDS |
CCDS34588
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HPRD |
12333
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IMGT |
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EMBL |
AB051478
AB162931
AC006028
AC073462
AK074158
AK124608
BC131824
BC152447
BE263005
CH236953
CH471144
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GenPept |
AAI31825
AAI52448
BAB21782
BAB84984
BAC85898
BAD20190
EAL23958
EAW87266
EAW87267
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