Homo sapiens Protein: NAT14
Summary
InnateDB Protein IDBP-70802.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAT14
Protein Name N-acetyltransferase 14 (GCN5-related, putative)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000205194
InnateDB Gene IDBG-70800 (NAT14)
Protein Structure
UniProt Annotation
Function Probable acetyltransferase that binds the 5'-GGACTACAG- 3' sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in K-562 and HeLa cell lines and in brain. {ECO:0000269PubMed:10873651}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008080 N-acetyltransferase activity
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000182 GNAT domain
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WUY8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 57106
UniGene Hs.743517
RefSeq NP_065111
HUGO HGNC:28918
OMIM
CCDS CCDS12926
HPRD 10036
IMGT
EMBL AB038651 AB055059 BC019079
GenPept AAH19079 BAB03716 BAB85857