InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CGRRF1

Summary

InnateDB Protein

IDBP-7083.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CGRRF1

Protein Name

cell growth regulator with ring finger domain 1

Synonyms

CGR19; RNF197;

Species

Homo sapiens

Ensembl Protein

ENSP00000216420

InnateDB Gene

IDBG-7081 (CGRRF1)

Protein Structure

UniProt Annotation

Function

Able to inhibit growth in several cell lines. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:22361696}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006950	response to stress
GO:0007050	cell cycle arrest
GO:0008285	negative regulation of cell proliferation

Cellular Component

GO:0005634	nucleus
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR001841 Zinc finger, RING-type

PFAM

PF13639
PF14634

PRINTS

PIRSF

SMART

SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99675

PhosphoSite

PhosphoSite-Q99675

TrEMBL

UniProt Splice Variant

Entrez Gene

10668

UniGene

Hs.602219

RefSeq

NP_006559

HUGO

HGNC:15528

OMIM

606138

CCDS

CCDS9719

HPRD

09366

IMGT

EMBL

BC015063 U66469

GenPept

AAC50897 AAH15063