Version 5.4
Homo sapiens Protein: LAYN
Summary
InnateDB Protein IDBP-70840.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LAYN
Protein Name layilin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000364764
InnateDB Gene IDBG-70836 (LAYN)
Protein Structure
UniProt Annotation
Function Receptor for hyaluronate. {ECO:0000269PubMed:11294894}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Colocalizes with TLN1 at the membrane ruffles. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005540 hyaluronic acid binding
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0001726 ruffle
GO:0009986 cell surface
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UX15
PhosphoSite PhosphoSite-Q6UX15
TrEMBL E9PQY8
UniProt Splice Variant
Entrez Gene 143903
UniGene Hs.503831
RefSeq NP_849156
HUGO HGNC:29471
OMIM
CCDS CCDS31676
HPRD 17299
IMGT
EMBL AK055539 AK055654 AK293317 AK296231 AP002008 AY358554 BC025407 CH471065
GenPept AAH25407 AAQ88918 BAB70946 BAB70978 BAG56836 BAG58952 EAW67145

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca