Version 5.4
Mus musculus Protein: Foxn3
Summary
InnateDB Protein IDBP-711790.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxn3
Protein Name
Synonyms 5430426H20Rik; AA589593; AW556347; Ches1; Ches1l; HTLFL1;
Species Mus musculus
Ensembl Protein ENSMUSP00000135082
InnateDB Gene IDBG-163381 (Foxn3)
Protein Structure
UniProt Annotation
Function Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity). {ECO:0000250UniProtKB:O00409}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008022 protein C-terminus binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1918625
InterPro IPR001766 Transcription factor, fork head
PFAM PF00250
PRINTS PR00053
PIRSF
SMART SM00339
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q499D0
PhosphoSite PhosphoSite-Q499D0
TrEMBL H3BLJ5
UniProt Splice Variant
Entrez Gene 71375
UniGene Mm.421593
RefSeq XP_006516295
MGI ID
MGI Symbol Foxn3
OMIM
CCDS CCDS26103
HPRD
IMGT
EMBL AC125409 AC125535 AC134604 AK017346 AK077921 BC099971
GenPept AAH99971 BAB30701 BAC37064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca