InnateDB Protein
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IDBP-7119.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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AMZ1
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Protein Name
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archaelysin family metallopeptidase 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000308149
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InnateDB Gene
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IDBG-7117 (AMZ1)
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Protein Structure
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Function |
Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2. {ECO:0000269PubMed:15972818}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Predominantly expressed in heart and liver. Also expressed at lower level in kidney, pancreas and testis. Expressed in fetal tissues such as kidney, liver, lung and brain. {ECO:0000269PubMed:15972818}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR012962
Peptidase M54, archaemetzincin
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PFAM |
PF07998
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q400G9
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PhosphoSite |
PhosphoSite-Q400G9
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TrEMBL |
B4DIY9
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UniProt Splice Variant |
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Entrez Gene |
155185
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UniGene |
Hs.436046
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RefSeq |
NP_597720
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HUGO |
HGNC:22231
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OMIM |
615168
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CCDS |
CCDS34589
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HPRD |
17232
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IMGT |
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EMBL |
AB075830
AC006028
AJ635357
AK092107
AK289723
AK295842
BC146753
CH236953
CH471144
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GenPept |
AAI46754
BAB85536
BAF82412
BAG52482
BAG58651
CAG25749
EAL23959
EAW87269
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