Version 5.4
Mus musculus Protein: Rnaset2b
Summary
InnateDB Protein IDBP-713294.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnaset2b
Protein Name
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000137303
InnateDB Gene IDBG-703030 (Rnaset2b)
Protein Structure
UniProt Annotation
Function Has ribonuclease activity, with higher activity at acidic pH. May play a role in cellular RNA catabolism. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}. Endoplasmic reticulum lumen {ECO:0000250}. Lysosome lumen {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004540 ribonuclease activity
GO:0033897 ribonuclease T2 activity
Biological Process
GO:0006401 RNA catabolic process
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005788 endoplasmic reticulum lumen
GO:0043202 lysosomal lumen
Protein Structure and Domains
PDB ID MGI:3702087
InterPro IPR001568 Ribonuclease T2-like
PFAM PF00445
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQ01
PhosphoSite PhosphoSite-Q9CQ01
TrEMBL Q9CVC3
UniProt Splice Variant
Entrez Gene 68195
UniGene Mm.482303
RefSeq XP_006523338
MGI ID
MGI Symbol Rnaset2b
OMIM
CCDS CCDS37429
HPRD
IMGT
EMBL AK008718 AK018722 AK019234 AK029149 AK052649 BC031496 BC089534 BC100330
GenPept AAH31496 AAH89534 AAI00331 BAB25853 BAB31368 BAB31616 BAC26326 BAC35080

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca