Version 5.4
Mus musculus Protein: Ctgf
Summary
InnateDB Protein IDBP-713402.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ctgf
Protein Name
Synonyms Ccn2; fisp-12; Fisp12; Hcs24;
Species Mus musculus
Ensembl Protein ENSMUSP00000135212
InnateDB Gene IDBG-138628 (Ctgf)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001968 fibronectin binding
GO:0005178 integrin binding
GO:0005520 insulin-like growth factor binding
GO:0008083 growth factor activity
GO:0008201 heparin binding
Biological Process
GO:0001502 cartilage condensation
GO:0001503 ossification
GO:0001525 angiogenesis
GO:0001558 regulation of cell growth
GO:0001894 tissue homeostasis
GO:0001934 positive regulation of protein phosphorylation
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009749 response to glucose
GO:0010260 organ senescence
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010942 positive regulation of cell death
GO:0016477 cell migration
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0032330 regulation of chondrocyte differentiation
GO:0032355 response to estradiol
GO:0032967 positive regulation of collagen biosynthetic process
GO:0034059 response to anoxia
GO:0035556 intracellular signal transduction
GO:0035988 chondrocyte proliferation
GO:0043200 response to amino acid
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043434 response to peptide hormone
GO:0045597 positive regulation of cell differentiation
GO:0046330 positive regulation of JNK cascade
GO:0050867 positive regulation of cell activation
GO:0051385 response to mineralocorticoid
GO:0051496 positive regulation of stress fiber assembly
GO:0060401 cytosolic calcium ion transport
GO:0060452 positive regulation of cardiac muscle contraction
GO:0060548 negative regulation of cell death
GO:0061448 connective tissue development
GO:0070278 extracellular matrix constituent secretion
GO:0070318 positive regulation of G0 to G1 transition
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070542 response to fatty acid
GO:0072593 reactive oxygen species metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:95537
InterPro IPR000867 Insulin-like growth factor-binding protein, IGFBP
PFAM PF00219
PRINTS
PIRSF
SMART SM00121
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BK14
UniProt Splice Variant
Entrez Gene 14219
UniGene Mm.392337
RefSeq
MGI ID
MGI Symbol Ctgf
OMIM
CCDS
HPRD
IMGT
EMBL AC099695
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca