Version 5.4
Mus musculus Protein: Tnnt2
Summary
InnateDB Protein IDBP-713760.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnnt2
Protein Name
Synonyms cTnT; Tnt;
Species Mus musculus
Ensembl Protein ENSMUSP00000137093
InnateDB Gene IDBG-195088 (Tnnt2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005523 tropomyosin binding
GO:0016887 ATPase activity
GO:0030172 troponin C binding
GO:0031013 troponin I binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006936 muscle contraction
GO:0006937 regulation of muscle contraction
GO:0007507 heart development
GO:0008016 regulation of heart contraction
GO:0030049 muscle filament sliding
GO:0032780 negative regulation of ATPase activity
GO:0032781 positive regulation of ATPase activity
GO:0045214 sarcomere organization
GO:0051592 response to calcium ion
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0055010 ventricular cardiac muscle tissue morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005861 troponin complex
GO:0030016 myofibril
GO:0030017 sarcomere
Protein Structure and Domains
PDB ID MGI:104597
InterPro IPR001978 Troponin
PFAM PF00992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6P3Z7
UniProt Splice Variant
Entrez Gene 21956
UniGene Mm.247470
RefSeq
MGI ID
MGI Symbol Tnnt2
OMIM
CCDS CCDS48375
HPRD
IMGT
EMBL AC162441 AK146945 BC063753
GenPept AAH63753 BAE27554

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca