Version 5.4
Mus musculus Protein: Zfp131
Summary
InnateDB Protein IDBP-714256.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp131
Protein Name
Synonyms 2610109I01Rik; AW558871; Znf131;
Species Mus musculus
Ensembl Protein ENSMUSP00000136867
InnateDB Gene IDBG-705077 (Zfp131)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling (By similarity). Plays a role during development and organogenesis as well as in the function of the adult central nervous system. {ECO:0000250, ECO:0000269PubMed:12163020}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed. Predominant expression is found in the developing central nervous system with strongest signals in the forebrain, midbrain, and hindbrain areas and in the neural tube. {ECO:0000269PubMed:12163020}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1919715
InterPro IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PF00651
PRINTS
PIRSF
SMART SM00225
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K3J5
PhosphoSite PhosphoSite-Q8K3J5
TrEMBL
UniProt Splice Variant
Entrez Gene 72465
UniGene Mm.403246
RefSeq XP_006517829
MGI ID
MGI Symbol Zfp131
OMIM
CCDS
HPRD
IMGT
EMBL AK011832 AK030398 AK047429 AK134257 AK135723 AK162903 AY092766 BC048839 BC057991
GenPept AAH48839 AAH57991 AAM18207 BAB27867 BAC26943 BAC33056 BAE22067 BAE22629 BAE37106

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca