Version 5.4
Homo sapiens Protein: BCO2
Summary
InnateDB Protein IDBP-71461.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCO2
Protein Name beta-carotene oxygenase 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354338
InnateDB Gene IDBG-71455 (BCO2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0016116 carotenoid metabolic process
GO:0016119 carotene metabolic process
GO:0016121 carotene catabolic process
GO:0042573 retinoic acid metabolic process
GO:0042574 retinal metabolic process
GO:0051881 regulation of mitochondrial membrane potential
GO:0055114 oxidation-reduction process
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR004294 Carotenoid oxygenase
PFAM PF03055
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BYV7
PhosphoSite PhosphoSite-Q9BYV7
TrEMBL V9GYA9
UniProt Splice Variant
Entrez Gene 83875
UniGene Hs.728325
RefSeq NP_001243327
HUGO HGNC:18503
OMIM 611740
CCDS CCDS58181
HPRD 12522
IMGT
EMBL AF276432 AJ290393 AK027801 AK297853 AP002884 BC041656 CH471065 EF444956
GenPept AAH41656 AAK69433 ACA05950 ACA05952 BAB55379 BAG60185 CAC27994 EAW67192

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca