Version 5.4
Mus musculus Protein: Ubl4
Summary
InnateDB Protein IDBP-714888.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubl4
Protein Name
Synonyms DXHXS254E; DXS254E; DXS254Eh; Gdx; Ubl4a;
Species Mus musculus
Ensembl Protein ENSMUSP00000136070
InnateDB Gene IDBG-156276 (Ubl4)
Protein Structure
UniProt Annotation
Function Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 238 interaction(s) predicted by orthology.
Predicted by orthology
Total 238 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005829 cytosol
GO:0071818 BAT3 complex
Protein Structure and Domains
PDB ID MGI:95049
InterPro IPR000626 Ubiquitin-like
IPR019956 Ubiquitin
IPR022617 Rad60/SUMO-like domain
IPR029071 Ubiquitin-related domain
PFAM PF00240
PF14560
PF11976
PRINTS PR00348
PIRSF
SMART SM00213
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21126
PhosphoSite PhosphoSite-P21126
TrEMBL Q91V47
UniProt Splice Variant
Entrez Gene 27643
UniGene Mm.3979
RefSeq NP_001265201
MGI ID
MGI Symbol Ubl4
OMIM
CCDS CCDS30230
HPRD
IMGT
EMBL AB039174 AB039175 AB039176 AB039177 AB039178 AB039179 AB039180 AB039181 AB039182 AJ627038 AK146110 BC010817 CH466650 J04761
GenPept AAA40520 AAH10817 BAB68698 BAB68699 BAB68700 BAB68701 BAB68702 BAB68703 BAB68704 BAB68705 BAB68706 BAE26908 CAF25307 EDL29818

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca